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KMID : 1123920040180020575
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Korean Journal of Oriental Physiology and Pathology
2004 Volume.18 No. 2 p.575 ~ p.579
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Antifungal Activity of 4-Geranyloxy Compound on the Dermatophytic Fungus
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Oh Hyun-Ju
You Byung-Soo
Kim Myung-Ju
Na Young-Soon
Kim Hyung-Min
Baek Seung-Hwa
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Abstract
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4-Geranyloxy compound (1) has elucidated by spectroscopic analysis. This compound (1) inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (2 mm inhibition zone at 15 ㎍/disc), cytotoxic to P388 murine leukaemia eel/lines ATCC CCL 46 P388D1, (IC/sub 50/ 1,125 ng/ml at 7.5㎍/disc) and BSC monkey kidney cell lines (100% of well at 15 ㎍/disc).
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KEYWORD
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4-Geranyloxy compound(1), Trichophyton mentagrophytes, P388, cytotoxic activity
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